ADEX Dental Hygiene Licensing Exam 2026 – Complete All-In-One Guide to Succeed

The defining histological feature of an odontogenic keratocyst (OKC) is the presence of keratinizing material within the cyst. This characteristic is significant because it distinguishes OKCs from other types of odontogenic cysts, which may not exhibit the same histological features. The epithelial lining of an OKC typically shows a stratified squamous epithelium that can undergo keratinization, leading to the accumulation of keratin within the cystic space. This keratinization can be associated with the aggressive behavior of OKCs and their higher recurrence rates compared to non-keratinizing odontogenic cysts.

The other features mentioned do not specifically define an OKC. Snowflake calcifications can occur in various conditions and are not exclusive to odontogenic keratocysts. The well-defined pear-shaped appearance and scalloped margins are more commonly associated with other types of odontogenic lesions, and while these features may present in some cases, they do not accurately characterize the histological profile unique to OKCs.